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PRJNA917819 SRP563843

Probiotics & post-antibiotic gut recovery, Chinese adults

Probiotics modulation of post-antibiotic gut microbiome in healthy population

296 gut microbiome samples from a healthy Chinese population, studying effects of three probiotic formulae on post-antibiotic recovery in an intervention design. machine-written summary

296 samples · 296 runs · CN · Age unknown · 2025 · 6.67 Gbp / sample

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Sources

✓Sequence archive 592✓Abstract / description 592–Full text–Supplementary tables–External resources–User contribution–Human verified

Checked this project's papers and archive records yourself? Mark it human-verified.

what each source gave

✓ Sequence archive	592 sample values (subject id, timepoint)
✓ Abstract / description	592 sample values (country, health condition)
– Full text	no open-access full text linked
– Supplementary tables	no supplementary tables available (or none open access)
– External resources	not covered by the external resources we ingest
– User contribution	nothing uploaded yet
– Human verified	not yet checked by a person · I checked this project — verify it

Interventions

intervention — arms not resolved

Probiotic (live microorganisms; single strain or mixture) design randomized_controlled_trial · population healthy_control · Three probiotic formulae given after antibiotic course to aid recovery

“three different formulae of probiotics on post-antibiotic recovery” — bioproject.description (study level; per-sample arms are in the intervention column below)

Samples at a glance

1 country

Age

unknown296

Condition

healthy_control296

Country

CN296

Body site

primary296

Sequencing depth per sample · this project all projects

Sampling design and relatedness

longitudinal

60 of 60 people sampled more than once (296 samples; median 5, up to 5 per person) · follow-up median 3 mo (max 3 mo) · median interval between samples 7 d (time from timepoint labels).

Each row is one person (36 shown of 60); dots are samples at days since that person's first sample.

How longitudinal and relatedness information is derived

Community composition

Bifidobacterium 12.7%Bacteroides 10.2%Blautia_A 8.2%Phocaeicola 8.2%Faecalibacterium 7.0%Collinsella 3.7%Mediterraneibacter 3.2%Roseburia 2.4%Parabacteroides 2.4%Fusicatenibacter 2.0%Escherichia 2.0%Alistipes 1.9%not assigned to a genus 3.7%other genera 32.4%

Genera, mean relative abundance over 254 profiled gut samples of this project (Sandpiper SingleM profiles, GTDB R232; low-depth and non-metagenome profiles left out).

Field coverage

field	samples	coverage	R1	R4
age_category	0	0%
country	296	100%		296
health_condition	296	100%		296
subject_id	296	100%	296
timepoint_label	296	100%	296

Details

Archive description

This study investigated the gut modulation effects of three different formulae of probiotics on post-antibiotic recovery in healthy Chinese population.

How this project entered the registry

Classified as human gut / stool shotgun DNA metagenome of age unknown by sonnet_x2 with confidence 0.75. Assay shotgun_dna.

host run.host_tax_id · “9606”
body site run.scientific_name · “human gut metagenome”

Evidence examples (one per field × route)

sample	field	value	route	conf.	source	quote
SAMN46797973	country	CN	R4	0.50	study.description	healthy Chinese population
SAMN46797973	health_condition	healthy_control	R4	0.50	study.description	healthy Chinese population
SAMN46797973	subject_id	MGA1	R1	0.70	sample.name_rule:title	MGA1_Day0
SAMN46797973	timepoint_label	Day0	R1	0.70	sample.name_rule:title	MGA1_Day0

Sequencing

296 runs over 296 samples · mean 6.66 Gbp per run (median 6.67 Gbp, total 1,972.26 Gbp; 296 runs with a base count) · layout PAIRED 296 · platform ILLUMINA 296 · models Illumina NovaSeq 6000 (296) · 86% of runs with a Sandpiper profile · first public 2025-02-15

Authors (0)

No author record.

Downloads

PRJNA917819.csv.gz (8.1 KB) · parquet (79.1 KB) — all 296 samples, every field with route and confidence · PRJNA917819_determinations.csv.gz (7.6 KB) — 1,184 evidence rows

Samples (296 · every field this project has values for · hover a cell for its source)

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