Gut microbiota and metabolites in adults with epilepsy

Identification of Gut Microbiota and Metabolites Signature in Patients With epilepsy

Shotgun metagenomic sequencing of feces from 32 samples from adults, studying gut microbiota and metabolite signatures associated with epilepsy. machine-written summary

32 samples · 32 runs · Adult · 2025 · 6.37 Gbp / sample

ENA BioProject Sample sheet Registry Download Flag an issue

Sources

✓Sequence archive 128○Abstract / description○Full text○Supplementary tables–External resources–User contribution–Human verified

Checked this project's papers and archive records yourself? Mark it human-verified.

what each source gave

✓ Sequence archive	128 sample values (age, health condition, health condition detail, sex)
○ Abstract / description	read; no usable statement
○ Full text	read; no usable statement or table · PMC10672912
○ Supplementary tables	files read; no table could be matched to the samples
– External resources	not covered by the external resources we ingest
– User contribution	nothing uploaded yet
– Human verified	not yet checked by a person · I checked this project — verify it

Samples at a glance

Age

adult32

Condition

neurological_psychiatric22

healthy_control10

Sex

female16

male16

Body site

primary32

Sequencing depth per sample · this project all projects

Community composition

Bifidobacterium 13.2%Faecalibacterium 7.3%Blautia_A 6.6%Roseburia 6.6%Bacteroides 5.5%Collinsella 3.8%Alistipes 3.8%Ruminococcoides 3.2%Dialister 2.9%Prevotella 2.7%Phocaeicola 2.5%Fusicatenibacter 2.4%not assigned to a genus 4.4%other genera 35.2%

Genera, mean relative abundance over 32 profiled gut samples of this project (Sandpiper SingleM profiles, GTDB R232; low-depth and non-metagenome profiles left out).

Field coverage

field	samples	coverage	R1
age_category	32	100%
country	0	0%
health_condition	32	100%	32
subject_id	0	0%
age_at_collection_days	32	100%	32
health_condition_detail	32	100%	32
sex	32	100%	32

Papers (1)

Integrated Macrogenomics and Metabolomics Explore Alterations and Correlation between Gut Microbiota and Serum Metabolites in Adult Epileptic Patients: A Pilot Study 2023 PMC10672912 unsure

Details

Archive description

normal macrogenomics sequencing of feces

How this project entered the registry

Classified as human gut / stool shotgun DNA metagenome of adult by deterministic_prior with confidence 0.90. Assay shotgun_dna.

host external_curation.infant_catalog · “infant triage reason_code age_adult_only”
body site study.title · “Identification of Gut Microbiota and Metabolites”
body site study.description · “macrogenomics sequencing of feces”
life stage external_curation.infant_catalog · “infant triage reason_code age_adult_only”

Evidence examples (one per field × route)

sample	field	value	route	conf.	source	quote
SAMN33591023	age_at_collection_days	9496.5	R1	0.85	sample.attr.age	26
SAMN33591023	health_condition	healthy_control	R1	0.70	sample.name_rule:library_names	N-1
SAMN33591023	health_condition_detail	N	R1	0.70	sample.name_rule:library_names	N-1
SAMN33591023	sex	male	R1	0.90	sample.attr.sex	male

Sequencing

32 runs over 32 samples · mean 6.39 Gbp per run (median 6.37 Gbp, total 204.40 Gbp; 32 runs with a base count) · layout SINGLE 32 · platform ILLUMINA 32 · models Illumina NovaSeq 6000 (32) · 100% of runs with a Sandpiper profile · first public 2025-05-28

Authors (7)

Zhou K first · Jia L · Mao Z · Si P · Sun C · Qu Z · Wang W last

Downloads

PRJNA941151.csv.gz (1.7 KB) · parquet (70.1 KB) — all 32 samples, every field with route and confidence · PRJNA941151_determinations.csv.gz (1.4 KB) — 128 evidence rows

Samples (32 · every field this project has values for · hover a cell for its source)

Loading the sample table…