Crohn's disease vs ulcerative colitis, Korea
Case-control study of 482 fecal metagenome samples from Korea (259 ulcerative colitis, 173 Crohn's disease, 50 healthy controls), using whole-metagenome shotgun sequencing to identify microbiome biomarkers distinguishing the two diseases. machine-written summary
482 samples · 482 runs · KR · Age unknown · 2023 · 6.48 Gbp / sample
Checked this project's papers and archive records yourself? Mark it human-verified.
what each source gave
| ✓ Sequence archive | 2,360 sample values (collection date, country, health condition, health condition detail, sex) |
| ○ Abstract / description | read; no usable statement |
| ✓ Full text | 482 sample values (location locality) · PMC10640746, PMC13354076 |
| ○ Supplementary tables | files read; no table could be matched to the samples |
| – External resources | not covered by the external resources we ingest |
| – User contribution | nothing uploaded yet · share metadata |
| – Human verified | not yet checked by a person · I checked this project — verify it |
No Sandpiper profile for this project's samples yet.
| field | samples | coverage | R1 | R2 | R3 | R4 |
|---|---|---|---|---|---|---|
| age_category | 0 | 0% | ||||
| country | 482 | 100% | 482 | |||
| health_condition | 482 | 100% | 482 | |||
| subject_id | 0 | 0% | ||||
| collection_date | 482 | 100% | 482 | |||
| detailed_location | 482 | 100% | ||||
| health_condition_detail | 482 | 100% | 482 | |||
| location_locality | 482 | 100% | 482 | |||
| sex | 432 | 90% | 432 |
- Diagnosis of Crohn's disease and ulcerative colitis using the microbiome. 2023 PMID 37951857 PMC10640746 own_data
- Integrative metagenomics and structural bioinformatics identify explainable gut microbial variants associated with Crohn's disease. 2026 PMID 42430408 PMC13354076 own_data
Archive description
Microbiological difference between Crohn's disease and ulcerative colitis
How this project entered the registry
Classified as human gut / stool shotgun DNA metagenome of age unknown by sonnet_x2 with confidence 0.68. Assay shotgun_dna.
- host run.scientific_name · “human gut metagenome”
- body site run.scientific_name · “human gut metagenome”
Evidence examples (one per field × route)
| sample | field | value | route | conf. | source | quote |
|---|---|---|---|---|---|---|
| SAMN33686270 | collection_date | 2020-08-28 | R1 | 0.90 | biosample.attribute:collection_date | 2020-08-28 |
| SAMN33686270 | country | KR | R1 | 0.90 | sample.attr.geo_loc_name | Korea |
| SAMN33686270 | health_condition | crohns_disease | R1 | 0.90 | biosample_attr | CD |
| SAMN33686270 | health_condition_detail | CD | R1 | 0.90 | sample.attr.host_disease | CD |
| SAMN33686270 | location_locality | Daejeon | R3 | 0.70 | paper.fulltext.methods | Daejeon St. Mary's Hospital |
| SAMN33686270 | sex | male | R1 | 0.90 | sample.attr.host_sex | male |
Sequencing
482 runs over 482 samples · mean 6.75 Gbp per run (median 6.48 Gbp, total 3,252.65 Gbp; 482 runs with a base count) · layout PAIRED 482 · platform BGISEQ 482 · models MGISEQ-2000RS (482) · 0% of runs with a Sandpiper profile · first public 2023-10-21
Authors (15)
Kang DY first · Park JL · Yeo MK · Kang SB · Kim JM · Kim JS · Kim SY last · Khan N first · Nasir MM · Aziz U · Manzoor H · Raziq MF · Hussain Z · Jabeen I · Kayani MUR last
Help complete this project
2 of the 4 core fields are below 50% coverage: age_category, subject_id. Share metadata
Downloads
PRJNA945504.csv.gz (11.2 KB) · parquet (86.6 KB) — all 482 samples, every field with route and confidence · PRJNA945504_determinations.csv.gz (11.8 KB) — 2,842 evidence rows