Gut microbiome in bullous pemphigoid vs controls, Germany
132 samples from bullous pemphigoid patients and age-, sex-, and study center-matched controls with non-inflammatory skin diseases, mainly elderly, collected across Germany, Bulgaria, and Finland in a case-control study. machine-written summary
132 samples · 132 runs · DE, BG, FI · Age unknown · 2023 · 6.43 Gbp / sample
Checked this project's papers and archive records yourself? Mark it human-verified.
what each source gave
| ✓ Sequence archive | 655 sample values (collection date, country, health condition, health condition detail, location locality) |
| ✓ Abstract / description | 132 sample values (subject id) |
| ✓ Full text | 135 sample values (antibiotic exposure, collection date) · PMC10668026 |
| ✓ Supplementary tables | 266 sample values (age, health condition, health condition detail, sex) |
| – External resources | not covered by the external resources we ingest |
| – User contribution | nothing uploaded yet |
| – Human verified | not yet checked by a person · I checked this project — verify it |
Genera, mean relative abundance over 123 profiled gut samples of this project (Sandpiper SingleM profiles, GTDB R232; low-depth and non-metagenome profiles left out).
| field | samples | coverage | R1 | R2 | R3 | R4 |
|---|---|---|---|---|---|---|
| age_category | 132 | 100% | ||||
| country | 132 | 100% | 132 | |||
| health_condition | 132 | 100% | 131 | 1 | ||
| subject_id | 132 | 100% | 132 | |||
| age_at_collection_days | 132 | 100% | 132 | |||
| antibiotic_exposure | 132 | 100% | 132 | |||
| collection_date | 132 | 100% | 129 | 3 | ||
| detailed_location | 132 | 100% | ||||
| health_condition_detail | 132 | 100% | 131 | 1 | ||
| location_locality | 132 | 100% | 132 | |||
| sex | 132 | 100% | 132 |
- The gut microbiome in bullous pemphigoid: implications of the gut-skin axis for disease susceptibility. 2023 PMID 38022583 PMC10668026 own_data
Archive description
The gut microbiome in bullous pemphigoid: implications of the gut-skin axis for disease susceptibility
How this project entered the registry
Classified as human gut / stool shotgun DNA metagenome of age unknown by sonnet_x2 with confidence 0.78. Assay shotgun_dna.
- host run.host_tax_id · “9606”
- body site run.scientific_name · “gut metagenome”
Evidence examples (one per field × route)
| sample | field | value | route | conf. | source | quote |
|---|---|---|---|---|---|---|
| SAMN34154367 | age_at_collection_days | 25202 | R2 | 0.85 | paper.supp.DataSheet_2.xlsx[Table S1!Age] | 69 |
| SAMN34154367 | antibiotic_exposure | no | R3 | 0.70 | paper.fulltext.methods | no antibiotic therapy four weeks prior to sampling |
| SAMN34154367 | collection_date | 2017-01-23 | R1 | 0.90 | biosample.attribute:collection_date | 2017-01-23 |
| SAMN34154390 | collection_date | 2015-06/2020-07 | R3 | 0.60 | paper.fulltext.results | from June 2015 to July 2020 |
| SAMN34154367 | country | DE | R1 | 0.90 | sample.attr.geo_loc_name | Germany: Dresden |
| SAMN34154367 | health_condition | other_disease | R1 | 0.70 | sample.name_rule:title | BP_DD_K150003 |
| SAMN34154429 | health_condition | healthy_control | R2 | 0.80 | paper.supp.DataSheet_2.xlsx[Table S1!Disease Status] | controls |
| SAMN34154367 | health_condition_detail | Non-inflammatory skin disease control e.g. basal/squamous cell carcinoma | R1 | 0.70 | sample.name_rule:title | BP_DD_K150003 |
| SAMN34154429 | health_condition_detail | controls | R2 | 0.85 | paper.supp.DataSheet_2.xlsx[Table S1!Disease Status] | controls |
| SAMN34154367 | location_locality | Dresden | R1 | 0.85 | biosample.attribute:geo_loc_name | Germany: Dresden |
| SAMN34154367 | sex | male | R2 | 0.85 | paper.supp.DataSheet_2.xlsx[Table S1!Gender] | Male |
| SAMN34154367 | subject_id | SAMN34154367 | R4 | 0.60 | design.one_sample_per_subject:abstract | 66 age-, sex-, and study center-matched controls (CL) with non-inflammatory skin diseases (132 total participants) |
Sequencing
132 runs over 132 samples · mean 7.31 Gbp per run (median 6.43 Gbp, total 964.79 Gbp; 132 runs with a base count) · layout PAIRED 132 · platform ILLUMINA 132 · models Illumina NovaSeq 6000 (132) · 93% of runs with a Sandpiper profile · first public 2023-10-30
Authors (28)
Liu X first · van Beek N · Cepic A · Andreani NA · Chung CJ · Hermes BM · Yilmaz K · Benoit S · Drenovska K · Gerdes S · Gläser R · Goebeler M · Günther C · von Georg A · Hammers CM · Holtsche MM · Hübner F · Kiritsi D · Schauer F · Linnenmann B · Huilaja L · Tasanen-Määttä K · Vassileva S · Zillikens D · Sadik CD · Schmidt E · Ibrahim S · Baines JF last
Downloads
PRJNA954584.csv.gz (5.5 KB) · parquet (77.8 KB) — all 132 samples, every field with route and confidence · PRJNA954584_determinations.csv.gz (10.7 KB) — 1,188 evidence rows