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PRJNA988170 SRP446336

Gut metagenome in recurrent acute pancreatitis, China

human gut metagenome Raw sequence reads

33 fecal metagenome samples from Shanghai, China, collected in a cross-sectional study of recurrent acute pancreatitis and its association with gut microbial species and metabolic pathways. machine-written summary

33 samples · 33 runs · CN · Adult · 2025 · 7.84 Gbp / sample

Sources
✓Sequence archive 165○Abstract / description○Full text○Supplementary tables–External resources–User contribution–Human verified

Checked this project's papers and archive records yourself? Mark it human-verified.

what each source gave
✓ Sequence archive165 sample values (age, collection date, country, location region, sex)
○ Abstract / descriptionread; no usable statement
○ Full textread; no usable statement or table · PMC12660694
○ Supplementary tablesfiles read; no table could be matched to the samples
– External resourcesnot covered by the external resources we ingest
– User contributionnothing uploaded yet
– Human verifiednot yet checked by a person · I checked this project — verify it
Interventions

intervention — arms not resolved

design observational_with_procedure · FMT enriched with F. prausnitzii; Fp strain/oleic acid in mouse AP models

Samples at a glance
1 country
Age
adult31
elderly2
Sex
male24
female9
Country
CN33
Body site
primary33
Collected 2020–2021
2020: 3 samples2021: 30 samples20202021
Sequencing depth per sample · this project all projects
all projects, 0–0.03 Gbp: 25,080 samples (4 %)all projects, 0.03–0.1 Gbp: 17,066 samples (3 %)all projects, 0.1–0.3 Gbp: 29,179 samples (5 %)all projects, 0.3–1 Gbp: 47,044 samples (8 %)all projects, 1–3 Gbp: 124,983 samples (22 %)all projects, 3–10 Gbp: 253,728 samples (44 %)this project, 3–10 Gbp: 31 samplesall projects, 10–30 Gbp: 72,533 samples (13 %)this project, 10–30 Gbp: 2 samplesall projects, 30–100 Gbp: 3,024 samples (1 %)all projects, 100–300 Gbp: 106 samples (0 %)all projects, ≥ 300 Gbp: 9 samples (0 %)project median 7.84 Gbp per sample0130Gbp
Community composition
Bacteroides 9.4%Faecalibacterium 8.1%Phocaeicola 7.0%Roseburia 3.6%Gemmiger 3.2%Blautia_A 3.0%Streptococcus 2.8%Alistipes 2.6%Mediterraneibacter 2.6%Megamonas 2.3%Dialister 2.2%Ruminococcoides 1.9%not assigned to a genus 5.0%other genera 46.3%

Genera, mean relative abundance over 33 profiled gut samples of this project (Sandpiper SingleM profiles, GTDB R232; low-depth and non-metagenome profiles left out).

Field coverage
fieldsamplescoverageR1R2R3R4
age_category33 100%
country33 100%33
health_condition0 0%
subject_id0 0%
age_at_collection_days33 100%33
collection_date33 100%33
detailed_location33 100%
location_region33 100%33
sex33 100%33
Papers (1)
  • Faecalibacterium prausnitzii alleviates experimental recurrent acute pancreatitis by producing oleic acid to regulate MAPK/NF-κB signaling and Th17/Treg balance. 2025 PMID 41271774 PMC12660694 own_data
Details
Archive description

normal metagenome of human fecal

How this project entered the registry

Classified as human gut / stool shotgun DNA metagenome of adult by sonnet_x2 with confidence 0.65. Assay shotgun_dna.

  • host run.scientific_name · “Homo sapiens”
  • body site study.description · “normal metagenome of human fecal”
  • life stage sample.attr.age · “38 (n=30/33)”
Evidence examples (one per field × route)
samplefieldvaluerouteconf.sourcequote
SAMN36003726age_at_collection_days10227.0R10.70sample.attr.age28
SAMN36003726collection_date2021-06R10.90biosample.attribute:collection_date2021-06
SAMN36003726countryCNR10.90sample.attr.geo_loc_nameChina:Shanghai
SAMN36003726location_regionShanghaiR10.85biosample.attribute:geo_loc_nameChina:Shanghai
SAMN36003726sexfemaleR10.90sample.attr.sexfemale
Sequencing

33 runs over 33 samples · mean 8.00 Gbp per run (median 7.84 Gbp, total 264.06 Gbp; 33 runs with a base count) · layout SINGLE 33 · platform ILLUMINA 33 · models Illumina NovaSeq 6000 (33) · 100% of runs with a Sandpiper profile · first public 2025-11-01

Authors (10)

Qin W first · Mei Q · Wang G · Wang R · Huang Z · Fu Y · Xu B · Huang C · Ai L · Zeng Y last

Downloads

PRJNA988170.csv.gz (1.9 KB) · parquet (70.6 KB) — all 33 samples, every field with route and confidence · PRJNA988170_determinations.csv.gz (1.6 KB) — 165 evidence rows

Samples (33 · every field this project has values for · hover a cell for its source)
Loading the sample table…