Diet soda intervention gut microbiome, Washington DC
82 gut microbiome samples from Washington, DC, USA, studying a diet soda (sucralose and acesulfame-potassium) intervention and its association with microbial taxa linked to inflammation and metabolic disease. machine-written summary
82 samples · 82 runs · US · Age unknown · 2023 · 0.25 Gbp / sample
Checked this project's papers and archive records yourself? Mark it human-verified.
what each source gave
| ✓ Sequence archive | 573 sample values (collection date, country, latitude, location region, longitude, subject id, timepoint) |
| – Abstract / description | no abstract or project description |
| – Full text | no open-access full text linked |
| – Supplementary tables | no supplementary tables available (or none open access) |
| – External resources | not covered by the external resources we ingest |
| – User contribution | nothing uploaded yet · share metadata |
| – Human verified | not yet checked by a person · I checked this project — verify it |
intervention — arms not resolved
Controlled / prescribed diet or feeding regimen design single_arm_before_after · population healthy_control · Diet soda (sucralose/acesulfame-K) consumption, before/after gut microbiome comparison
“Consumption of sucralose and acesulfame-potassium containing diet soda” — bioproject.description (study level; per-sample arms are in the intervention column below)
longitudinal
28 of 28 people sampled more than once (82 samples; median 3, up to 3 per person) · follow-up median 14 d (max 7.0 y) · median interval between samples 7 d (time from collection dates).
Each row is one person (28 shown); dots are samples at days since that person's first sample.
Genera, mean relative abundance over 60 profiled gut samples of this project (Sandpiper SingleM profiles, GTDB R232; low-depth and non-metagenome profiles left out).
| field | samples | coverage | R1 | R2 | R3 | R4 |
|---|---|---|---|---|---|---|
| age_category | 0 | 0% | ||||
| country | 82 | 100% | 82 | |||
| health_condition | 0 | 0% | ||||
| subject_id | 82 | 100% | 82 | |||
| collection_date | 82 | 100% | 82 | |||
| detailed_location | 82 | 100% | ||||
| latitude | 82 | 100% | 82 | |||
| location_region | 82 | 100% | 82 | |||
| longitude | 82 | 100% | 82 | |||
| timepoint_label | 81 | 99% | 81 |
Archive description
Consumption of sucralose and acesulfame-potassium containing diet soda alters the relative abundance of microbial taxa implicated in inflammation and metabolic disease
How this project entered the registry
Classified as human gut / stool shotgun DNA metagenome of age unknown by sonnet_x2 with confidence 0.65. Assay shotgun_dna.
- host run.host_tax_id · “9606”
- host run.scientific_name · “human gut metagenome”
- body site study.title · “Diet Soda Human gut microbiome”
Evidence examples (one per field × route)
| sample | field | value | route | conf. | source | quote |
|---|---|---|---|---|---|---|
| SAMN36463836 | collection_date | 2015-04-21 | R1 | 0.90 | biosample.attribute:collection_date | 2015-04-21 |
| SAMN36463836 | country | US | R1 | 0.90 | sample.attr.geo_loc_name | USA: District of Columbia |
| SAMN36463836 | latitude | 38.9062 | R1 | 0.90 | biosample.attribute:lat_lon | 38.9062 N 77.0369 W |
| SAMN36463836 | location_region | District of Columbia | R1 | 0.85 | biosample.attribute:geo_loc_name | USA: District of Columbia |
| SAMN36463836 | longitude | -77.0369 | R1 | 0.90 | biosample.attribute:lat_lon | 38.9062 N 77.0369 W |
| SAMN36463836 | subject_id | NNS01 | R1 | 0.85 | sample.attr.host_subject_id | NNS01 |
| SAMN36463836 | timepoint_label | 1 | R1 | 0.70 | sample.name_rule:alias | NNS-01-1 |
Sequencing
82 runs over 82 samples · mean 1.95 Gbp per run (median 0.25 Gbp, total 159.73 Gbp; 82 runs with a base count) · layout PAIRED 82 · platform ILLUMINA 82 · models NextSeq 500 (82) · 73% of runs with a Sandpiper profile · first public 2023-07-16
Authors (0)
No author record.
Help complete this project
2 of the 4 core fields are below 50% coverage: age_category, health_condition. Share metadata
Downloads
PRJNA995034.csv.gz (3.2 KB) · parquet (73.8 KB) — all 82 samples, every field with route and confidence · PRJNA995034_determinations.csv.gz (4.8 KB) — 573 evidence rows