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Liver cirrhosis cohorts
Disease reference sets · collection id liver-cirrhosis-cohorts
Shotgun cohorts of liver cirrhosis: the Chinese case–control cohort of Qin 2014 (the cirrhosis MWAS), the MICROB-PREDICT decompensated-cirrhosis deposit and the PROFIT FMT-in-cirrhosis trial. Pair with the liver_disease health-condition filter for all liver-disease samples.
Open in the sample explorer (892 samples)
3
studies with member samples
892
member samples in this release
Membership rule
| Studies | PRJEB6337, PRJEB89898, PRJEB61882 |
Composition
Age category
| adult | 872 |
| elderly | 20 |
Country
| CN | 312 |
| HU | 302 |
| GB | 278 |
Health condition
| liver_disease Liver disease (cirrhosis | 749 |
| healthy_control Healthy / control | 143 |
Member studies (3)
| Study | Title | Member samples | First public |
|---|---|---|---|
| PRJEB6337 | Liver cirrhosis occurs as a consequence of many chronic liver diseases that are prevalent worldwide. Previous studies have shown an association between the gut microbiota and liver complications such as cirrhosis and other liver injuries. We therefore undertook a whole gut microbiome wide association study of stool samples from 98 liver cirrhosis patients and 83 healthy controls to characterise the faecal microbial communities and their functional composition. In total, we generated 860 Gb of high-quality sequence data and built a reference gene set for the liver cirrhosis cohort containing 2.69 million genes, 36.1% of which was not covered by previously published gene catalogues. | 312 | 2014 |
| PRJEB89898 | Metagenomic sequences of the fecal microbiome from patients with decompensated cirrhosis and ACLF | 302 | 2025 |
| PRJEB61882 | PROFIT Trial: FMT in cirrhosis | 278 | 2024 |