Gut microbiome/virome in pediatric nephrotic syndrome
123 samples from children, examining gut microbiome and virome dysbiosis in idiopathic nephrotic syndrome. No further details on location, condition breakdown, or design are given. machine-written summary
123 samples · 123 runs · Child · 2026 · 0.61 Gbp / sample
One study deposited as 2 BioProjects (245 catalog samples together): PRJNA1295133 · PRJNA1295840 · show together
Checked this project's papers and archive records yourself? Mark it human-verified.
what each source gave
| ✓ Sequence archive | 453 sample values (health condition, health condition detail, subject id, timepoint) |
| – Abstract / description | no abstract or project description |
| – Full text | no open-access full text linked |
| – Supplementary tables | no supplementary tables available (or none open access) |
| – External resources | not covered by the external resources we ingest |
| – User contribution | nothing uploaded yet |
| – Human verified | not yet checked by a person · I checked this project — verify it |
longitudinal — not resolved
20 of 101 people sampled more than once (42 samples; median 2, up to 3 per person). Schedule stated by the source: “NS patients sampled at up to three timepoints labeled T0, T1, T2 per DESCRIPTION/library_name; CTR (control) samples appear single timepoint only.”.
No Sandpiper profile for this project's samples yet.
| field | samples | coverage | R1 | R2 | R3 | R4 |
|---|---|---|---|---|---|---|
| age_category | 123 | 100% | ||||
| country | 0 | 0% | ||||
| health_condition | 123 | 100% | 123 | |||
| subject_id | 123 | 100% | 123 | |||
| health_condition_detail | 123 | 100% | 123 | |||
| timepoint_label | 84 | 68% | 84 |
Archive description
Idiopathic nephrotic syndrome (INS) is the most frequent glomerular disorder in children, yet its etiology remains unclear. Growing evidence implicates gut microbiome dysbiosis and immune dysregulation in its pathogenesis, but comprehensive multi-kingdom microbiome studies are lacking.
How this project entered the registry
Classified as human gut / stool shotgun DNA metagenome of child by sonnet_x2 with confidence 0.72. Assay shotgun_dna.
- host study.title · “Pediatric Idiopathic Nephrotic Syndrome”
- body site study.title · “Gut Microbiome and Virome Dysbiosis”
- life stage study.title · “Pediatric Idiopathic Nephrotic Syndrome”
Evidence examples (one per field × route)
| sample | field | value | route | conf. | source | quote |
|---|---|---|---|---|---|---|
| SAMN50152457 | health_condition | healthy_control | R1 | 0.70 | sample.name_rule:title | CTR.NS.001 |
| SAMN50152457 | health_condition_detail | CTR | R1 | 0.70 | sample.name_rule:title | CTR.NS.001 |
| SAMN50152457 | subject_id | CTR.NS.001 | R1 | 0.70 | sample.name_rule:run.library_name | CTR.NS.001 |
| SAMN50152476 | subject_id | NS.001 | R1 | 0.70 | sample.name_rule:title | NS.001.T1 |
| SAMN50152476 | timepoint_label | T1 | R1 | 0.70 | sample.name_rule:title | NS.001.T1 |
Sequencing
123 runs over 123 samples · mean 0.79 Gbp per run (median 0.61 Gbp, total 97.06 Gbp; 123 runs with a base count) · layout PAIRED 123 · platform ILLUMINA 123 · models Illumina MiSeq (123) · 0% of runs with a Sandpiper profile · first public 2026-06-17
Authors (0)
No author record.
Downloads
PRJNA1295133.csv.gz (3.9 KB) · parquet (74.0 KB) — all 123 samples, every field with route and confidence · PRJNA1295133_determinations.csv.gz (5.4 KB) — 453 evidence rows