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PRJNA1295840 SRP603753

Pediatric nephrotic syndrome gut microbiome and virome

Gut Microbiome and Virome Dysbiosis in Pediatric Idiopathic Nephrotic Syndrome: A Multi-Kingdom Disruption of Microbial Crosstalk

122 samples from children, examining gut microbiome and virome dysbiosis in idiopathic nephrotic syndrome. No further details on location, design, or health conditions are given. machine-written summary

122 samples · 122 runs · Child · 2026 · 0.76 Gbp / sample

One study deposited as 2 BioProjects (245 catalog samples together): PRJNA1295133 · PRJNA1295840 · show together

Sources
✓Sequence archive 405–Abstract / description–Full text–Supplementary tables–External resources–User contribution–Human verified

Checked this project's papers and archive records yourself? Mark it human-verified.

what each source gave
✓ Sequence archive405 sample values (health condition, health condition detail, subject id, timepoint)
– Abstract / descriptionno abstract or project description
– Full textno open-access full text linked
– Supplementary tablesno supplementary tables available (or none open access)
– External resourcesnot covered by the external resources we ingest
– User contributionnothing uploaded yet · share metadata
– Human verifiednot yet checked by a person · I checked this project — verify it
Samples at a glance
Age
child122
Condition
kidney_disease82
healthy_control40
Body site
primary122
Sequencing depth per sample · this project all projects
all projects, 0–0.03 Gbp: 25,080 samples (4 %)all projects, 0.03–0.1 Gbp: 17,066 samples (3 %)this project, 0.03–0.1 Gbp: 3 samplesall projects, 0.1–0.3 Gbp: 29,179 samples (5 %)this project, 0.1–0.3 Gbp: 3 samplesall projects, 0.3–1 Gbp: 47,044 samples (8 %)this project, 0.3–1 Gbp: 87 samplesall projects, 1–3 Gbp: 124,983 samples (22 %)this project, 1–3 Gbp: 27 samplesall projects, 3–10 Gbp: 253,728 samples (44 %)this project, 3–10 Gbp: 2 samplesall projects, 10–30 Gbp: 72,533 samples (13 %)all projects, 30–100 Gbp: 3,024 samples (1 %)all projects, 100–300 Gbp: 106 samples (0 %)all projects, ≥ 300 Gbp: 9 samples (0 %)project median 0.76 Gbp per sample0130Gbp
Sampling design and relatedness

longitudinal — not resolved

Schedule stated by the source: “Patient samples coded with timepoint suffixes T0/T1/T2 per subject (e.g., V.NS.043.T0, V.NS.043.T2); controls have single samples.”.

How longitudinal and relatedness information is derived

Community composition

No Sandpiper profile for this project's samples yet.

Field coverage
fieldsamplescoverageR1R2R3R4
age_category122 100%
country0 0%
health_condition122 100%122
subject_id39 32%39
health_condition_detail122 100%122
timepoint_label122 100%122
Details
Archive description

Idiopathic nephrotic syndrome (INS) is the most frequent glomerular disorder in children, yet its etiology remains unclear. Growing evidence implicates gut microbiome dysbiosis and immune dysregulation in its pathogenesis, but comprehensive multi-kingdom microbiome studies are lacking.

How this project entered the registry

Classified as human gut / stool shotgun DNA metagenome of child by sonnet_x2 with confidence 0.62. Assay shotgun_dna.

  • host study.title · “Gut Microbiome and Virome Dysbiosis in Pediatric”
  • body site study.title · “Gut Microbiome and Virome Dysbiosis”
  • life stage study.title · “Pediatric Idiopathic Nephrotic Syndrome”
Evidence examples (one per field × route)
samplefieldvaluerouteconf.sourcequote
SAMN50191465health_conditionhealthy_controlR10.85biosample.attribute:descriptiondescription: CTR
SAMN50191465health_condition_detailCTRR10.85biosample.attribute:descriptiondescription: CTR
SAMN50191465subject_idCTR.NS.001R10.70sample.name_rule:biosample.titleCTR.NS.01 / V.CTR.NS.001
SAMN50191465timepoint_labelCTRR10.85biosample.attribute:descriptiondescription: CTR
Sequencing

122 runs over 122 samples · mean 0.90 Gbp per run (median 0.76 Gbp, total 110.33 Gbp; 122 runs with a base count) · layout PAIRED 122 · platform ILLUMINA 122 · models Illumina MiSeq (122) · 0% of runs with a Sandpiper profile · first public 2026-06-17

Authors (0)

No author record.

Help complete this project

2 of the 4 core fields are below 50% coverage: country, subject_id. Share metadata

Downloads

PRJNA1295840.csv.gz (3.7 KB) · parquet (73.8 KB) — all 122 samples, every field with route and confidence · PRJNA1295840_determinations.csv.gz (3.8 KB) — 405 evidence rows

Samples (122 · every field this project has values for · hover a cell for its source)
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