Gut microbiome in resectable HCC vs benign liver tumors, China
Shotgun metagenomic study of 197 catalog samples from a Chinese cohort (120 resectable hepatocellular carcinoma cases and 76 benign hepatic tumor controls) profiling gut microbiome composition and co-abundance network structure. machine-written summary
197 samples · 197 runs · CN · Age unknown · 2026 · 7.24 Gbp / sample · cohort Two stable gut microbiome guilds predict liver tum
One study deposited as 2 BioProjects (254 catalog samples together): PRJNA1372070 · PRJNA1372073 · show together
Checked this project's papers and archive records yourself? Mark it human-verified.
what each source gave
| ✓ Sequence archive | 394 sample values (collection date, country) |
| ○ Abstract / description | read; no usable statement |
| ✓ Full text | 197 sample values (antibiotic exposure) · PMC13147943 |
| ✓ Supplementary tables | 392 sample values (health condition, health condition detail) |
| – External resources | not covered by the external resources we ingest |
| – User contribution | nothing uploaded yet · share metadata |
| – Human verified | not yet checked by a person · I checked this project — verify it |
No Sandpiper profile for this project's samples yet.
| field | samples | coverage | R1 | R2 | R3 | R4 |
|---|---|---|---|---|---|---|
| age_category | 0 | 0% | ||||
| country | 197 | 100% | 197 | |||
| health_condition | 196 | 99% | 196 | |||
| subject_id | 0 | 0% | ||||
| antibiotic_exposure | 197 | 100% | 197 | |||
| collection_date | 197 | 100% | 197 | |||
| health_condition_detail | 196 | 99% | 196 |
- Two stable gut microbiome guilds predict liver tumor class and treatment responses. 2026 PMID 42099457 PMC13147943 own_data
Archive description
A dataset of 197 samples with HCC
How this project entered the registry
Classified as human gut / stool shotgun DNA metagenome of age unknown by curator_audit with confidence 0.40. Assay shotgun_dna.
- host runs.scientific_name · “human gut metagenome (197)”
- host runs.isolation_source · “feces (197)”
- body site runs.scientific_name · “human gut metagenome (197)”
- body site runs.isolation_source · “feces (197)”
Evidence examples (one per field × route)
| sample | field | value | route | conf. | source | quote |
|---|---|---|---|---|---|---|
| SAMN53528485 | antibiotic_exposure | no | R3 | 0.70 | paper.body.methods | were screened, with exclusions due to incomplete clinical data, recent systemic antibiotics/probiotics/prebiotics (within 3 months) |
| SAMN53528485 | collection_date | 2019-11-07 | R1 | 0.85 | biosample.attribute:collection_date | collection_date: 2019-11-07 |
| SAMN53528485 | country | CN | R1 | 0.90 | sample.attr.geo_loc_name | China: Shanghai |
| SAMN53528485 | health_condition | liver_disease | R2 | 0.85 | paper.supp.IMT2-5-e70123-s001.xlsx[S8!BT/MT] | PLC_66 BT |
| SAMN53528485 | health_condition_detail | benign hepatic tumor (BT), e.g. hepatic hemangioma | R2 | 0.85 | paper.supp.IMT2-5-e70123-s001.xlsx[S8!BT/MT] | PLC_66 BT |
Sequencing
197 runs over 197 samples · mean 7.37 Gbp per run (median 7.24 Gbp, total 1,452.75 Gbp; 197 runs with a base count) · layout PAIRED 197 · platform ILLUMINA 197 · models Illumina NovaSeq 6000 (197) · 0% of runs with a Sandpiper profile · first public 2026-03-23
Authors (0)
No author record.
Help complete this project
2 of the 4 core fields are below 50% coverage: age_category, subject_id. Share metadata
Downloads
PRJNA1372070.csv.gz (5.9 KB) · parquet (77.6 KB) — all 197 samples, every field with route and confidence · PRJNA1372070_determinations.csv.gz (8.3 KB) — 983 evidence rows