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PRJNA808649 SRP360679

Gut microbiota in idiopathic short stature (children)

Alterations in the gut microbiota in people with idiopathic short stature

60 gut microbiome samples from children, infants, and adolescents, comparing idiopathic short stature patients with healthy controls; location not specified. machine-written summary

60 samples · 120 runs · CN · Child · 2024 · 6.65 Gbp / sample · cohort Gut microbiota and metabolic changes in children w

One study deposited as 2 BioProjects (111 catalog samples together): PRJNA808649 · PRJNA941095 · show together

Sources
✓Sequence archive 240–Abstract / description✓Full text 120–Supplementary tables✓External resources 60–User contribution–Human verified

Checked this project's papers and archive records yourself? Mark it human-verified.

what each source gave
✓ Sequence archive240 sample values (age, health condition, health condition detail, sex)
– Abstract / descriptionno abstract or project description
✓ Full text120 sample values (antibiotic exposure, collection date) · PMC11265363
– Supplementary tablesno supplementary tables available (or none open access)
✓ External resources60 sample values (country) · from GMrepo v3
– User contributionnothing uploaded yet
– Human verifiednot yet checked by a person · I checked this project — verify it
Samples at a glance
1 country
Age
child47
infant8
adolescent5
Condition
healthy_control30
other_disease30
Sex
male31
female29
Country
CN60
Body site
primary60
Sequencing depth per sample · this project all projects
all projects, 0–0.03 Gbp: 25,080 samples (4 %)all projects, 0.03–0.1 Gbp: 17,066 samples (3 %)all projects, 0.1–0.3 Gbp: 29,179 samples (5 %)all projects, 0.3–1 Gbp: 47,044 samples (8 %)all projects, 1–3 Gbp: 124,983 samples (22 %)all projects, 3–10 Gbp: 253,728 samples (44 %)this project, 3–10 Gbp: 60 samplesall projects, 10–30 Gbp: 72,533 samples (13 %)all projects, 30–100 Gbp: 3,024 samples (1 %)all projects, 100–300 Gbp: 106 samples (0 %)all projects, ≥ 300 Gbp: 9 samples (0 %)project median 6.65 Gbp per sample0130Gbp
Community composition
Bacteroides 16.0%Phocaeicola 12.2%Faecalibacterium 7.5%Bifidobacterium 7.3%Blautia_A 4.7%Roseburia 3.9%Alistipes 3.3%Parabacteroides 2.5%Mediterraneibacter 2.4%Ruminococcoides 2.0%Prevotella 1.7%Fusicatenibacter 1.7%not assigned to a genus 3.6%other genera 31.1%

Genera, mean relative abundance over 53 profiled gut samples of this project (Sandpiper SingleM profiles, GTDB R232; low-depth and non-metagenome profiles left out).

Field coverage
fieldsamplescoverageR1R2R3R4
age_category60 100%
country60 100%60
health_condition60 100%60
subject_id0 0%
age_at_collection_days60 100%60
antibiotic_exposure60 100%60
collection_date60 100%60
health_condition_detail60 100%60
sex60 100%60
Papers (1)
Details
Archive description

Our study presents a comprehensive profile of the gut microbiota in patients with ISS

How this project entered the registry

Classified as human gut / stool shotgun DNA metagenome of child by sonnet_x2 with confidence 0.72. Assay shotgun_dna.

  • host run.scientific_name · “human gut metagenome”
  • body site study.title · “gut microbiota in people”
  • life stage sample.attr.age · “4 (n=57/60)”
Evidence examples (one per field × route)
samplefieldvaluerouteconf.sourcequote
SAMN26096795age_at_collection_days1095.8R10.70sample.attr.age3
SAMN26096795antibiotic_exposurenoR30.70paper.fulltext.methodsUse of antibiotics, probiotics, hormones, proton pump inhibitors
SAMN26096795collection_date2019-09/2021-04R30.70paper.fulltext.methodsFrom September 2019 to April 2021, we recruited
SAMN26096795countryCNR20.75external.gmrepo sourcecountry: China
SAMN26096795health_conditionhealthy_controlR10.70sample.name_rule:sample_aliasC1
SAMN26096795health_condition_detailCR10.70sample.name_rule:sample_aliasC1
SAMN26096795sexfemaleR10.90sample.attr.sexfemale
Sequencing

120 runs over 60 samples · mean 3.33 Gbp per run (median 2.97 Gbp, total 399.44 Gbp; 120 runs with a base count) · layout PAIRED 120 · platform ILLUMINA 120 · models Illumina NovaSeq 6000 (120) · 44% of runs with a Sandpiper profile · first public 2024-03-24

Authors (0)

No author record.

Downloads

PRJNA808649.csv.gz (2.5 KB) · parquet (71.7 KB) — all 60 samples, every field with route and confidence · PRJNA808649_determinations.csv.gz (3.5 KB) — 420 evidence rows

Samples (60 · every field this project has values for · hover a cell for its source)
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