Gut microbiome in simple liver steatosis (MASLD), Austria
Shotgun metagenomic sequencing of 36 stool samples from an Austrian cohort collected in 2010, examining gut microbiome profiles in relation to simple liver steatosis in MASLD, with per-sample age and condition data not available in the archive. machine-written summary
36 samples · 36 runs · AT · Adult · 2026 · 5.28 Gbp / sample
One study deposited as 3 BioProjects (134 catalog samples together): PRJEB120967 · PRJEB120968 · PRJEB120969 · show together
Checked this project's papers and archive records yourself? Mark it human-verified.
what each source gave
| ✓ Sequence archive | 72 sample values (collection date, country) |
| ✓ Abstract / description | 36 sample values (location region) |
| – Full text | no open-access full text linked |
| – Supplementary tables | no supplementary tables available (or none open access) |
| – External resources | not covered by the external resources we ingest |
| – User contribution | nothing uploaded yet |
| – Human verified | not yet checked by a person · I checked this project — verify it |
No Sandpiper profile for this project's samples yet.
| field | samples | coverage | R1 | R2 | R3 | R4 |
|---|---|---|---|---|---|---|
| age_category | 36 | 100% | ||||
| country | 36 | 100% | 36 | |||
| health_condition | 0 | 0% | ||||
| subject_id | 0 | 0% | ||||
| collection_date | 36 | 100% | 36 | |||
| detailed_location | 36 | 100% | ||||
| location_region | 36 | 100% | 36 |
Archive description
This study contains whole-genome shotgun metagenomic sequencing data from faecal samples collected in the Austrian cohort of the study “Gut microbiome profiles associated with simple liver steatosis in MASLD”. The cohort includes adults with biopsy-confirmed simple steatosis and geographically matched controls without steatosis. Individuals with histological steatohepatitis, significant fibrosis, recent antibiotic use, proton pump inhibitor use, metformin use, or other relevant exclusion criteria were not included in the analysis. The aim of the study was to characterize gut microbiota composition and functional potential in simple steatosis, the earliest clinically relevant stage of metabolic dysfunction-associated steatotic liver disease (MASLD), while minimizing confounding by common medications. These data were analysed together with independent Swedish and Italian cohorts to assess microbiome signatures associated with simple steatosis across European populations spanning a broad range of body mass index.
How this project entered the registry
Classified as human gut / stool shotgun DNA metagenome of adult by sonnet_x2 with confidence 0.88. Assay shotgun_dna.
- host run.scientific_name · “Homo sapiens”
- body site study.description · “faecal samples collected in the Austrian cohort”
- life stage study.description · “The cohort includes adults with biopsy-confirmed”
Evidence examples (one per field × route)
| sample | field | value | route | conf. | source | quote |
|---|---|---|---|---|---|---|
| SAMEA123178912 | collection_date | 2010 | R1 | 0.85 | biosample.attribute:collection_date | 2010 |
| SAMEA123178912 | country | AT | R1 | 0.90 | sample.attr.geographic_location_country_and_or_sea | Austria |
| SAMEA123178912 | location_region | Austria | R4 | 0.40 | ena.study_title | Austrian cohort |
Sequencing
36 runs over 36 samples · mean 5.38 Gbp per run (median 5.28 Gbp, total 193.58 Gbp; 36 runs with a base count) · layout PAIRED 36 · platform ILLUMINA 36 · models NextSeq 500 (36) · 0% of runs with a Sandpiper profile · first public 2026-09-29
Authors (0)
No author record.
Downloads
PRJEB120969.csv.gz (1.7 KB) · parquet (69.9 KB) — all 36 samples, every field with route and confidence · PRJEB120969_determinations.csv.gz (935 B) — 108 evidence rows