GD intestinal microbiome case-control study, Haikou, China
20 samples from Haikou, China, from a case-control study of ecological and evolutionary changes in the intestinal microbiome in GD. machine-written summary
20 samples · 20 runs · CN · Age unknown · 2020 · 8.59 Gbp / sample
One study deposited as 6 BioProjects (164 catalog samples together): PRJNA602729 · PRJNA602731 · PRJNA602732 · PRJNA638403 · PRJNA638404 · PRJNA638405 · show together
Checked this project's papers and archive records yourself? Mark it human-verified.
what each source gave
| ✓ Sequence archive | 148 sample values (collection date, country, health condition, health condition detail, latitude, location locality, location region, longitude) |
| ○ Abstract / description | read; no usable statement |
| ○ Full text | read; no usable statement or table · PMC10734426, PMC11954268, PMC8528855 |
| ✓ Supplementary tables | 26 sample values (age, bmi, sex, smoking status) |
| ✓ External resources | 54 sample values (age, bmi, sex) · from Meta2DB (LLNL) |
| – User contribution | nothing uploaded yet |
| – Human verified | not yet checked by a person · I checked this project — verify it |
Genera, mean relative abundance over 17 profiled gut samples of this project (Sandpiper SingleM profiles, GTDB R232; low-depth and non-metagenome profiles left out).
| field | samples | coverage | R1 | R2 | R3 | R4 |
|---|---|---|---|---|---|---|
| age_category | 20 | 100% | ||||
| country | 20 | 100% | 20 | |||
| health_condition | 20 | 100% | 20 | |||
| subject_id | 0 | 0% | ||||
| age_at_collection_days | 20 | 100% | 20 | |||
| bmi | 20 | 100% | 20 | |||
| collection_date | 20 | 100% | 20 | |||
| detailed_location | 20 | 100% | ||||
| health_condition_detail | 20 | 100% | 20 | |||
| latitude | 20 | 100% | 20 | |||
| location_locality | 20 | 100% | 20 | |||
| longitude | 20 | 100% | 20 | |||
| sex | 20 | 100% | 20 | |||
| smoking_status | 20 | 100% | 20 | |||
| location_region | 8 | 40% | 8 |
- Compositional and genetic alterations in Graves' disease gut microbiome reveal specific diagnostic biomarkers. 2021 PMID 34079079 PMC8528855 unsure
- Cross-cohort single-nucleotide-variant profiling of gut microbiota suggests a novel gut-health assessment approach. 2023 PMID 37905808 PMC10734426 unsure
- Modeling microbiome-trait associations with taxonomy-adaptive neural networks. 2025 PMID 40158141 PMC11954268 unsure
Archive description
Ecological and evolutionary alteration in the GD intestinal microbiome
How this project entered the registry
Classified as human gut / stool shotgun DNA metagenome of age unknown by sonnet_x2 with confidence 0.60. Assay shotgun_dna.
- host run.host_tax_id · “9606”
- body site study.title · “GD intestinal microbiome”
Evidence examples (one per field × route)
| sample | field | value | route | conf. | source | quote |
|---|---|---|---|---|---|---|
| SAMN15195432 | age_at_collection_days | 16071.0 | R2 | 0.70 | external.meta2db source | host_age: 44 |
| SAMN15195433 | age_at_collection_days | 12053.2 | R2 | 0.80 | paper.supp.41396_2021_1016_MOESM2_ESM.xlsx[Table_S1!Age] | col0=C022; Age=33 |
| SAMN15195432 | bmi | 30.21 | R2 | 0.70 | external.meta2db source | host_body_mass_index: 30.21 kilogram per meter squared |
| SAMN15195433 | bmi | 18.71 | R2 | 0.80 | paper.supp.41396_2021_1016_MOESM2_ESM.xlsx[Table_S1!BMI] | col0=C022; BMI=18.71 |
| SAMN15195432 | collection_date | 2018-07 | R1 | 0.90 | biosample.attribute:collection_date | 2018-07 |
| SAMN15195432 | country | CN | R1 | 0.90 | sample.attr.geo_loc_name | China: Haikou |
| SAMN15195432 | health_condition | healthy_control | R1 | 0.85 | biosample.attribute:title | title: HC metagenome |
| SAMN15195432 | health_condition_detail | HC metagenome | R1 | 0.85 | biosample.attribute:title | title: HC metagenome |
| SAMN15195432 | latitude | 20.0300 | R1 | 0.90 | biosample.attribute:lat_lon | 20.03 N 110.10 E |
| SAMN15195432 | location_locality | Haikou | R1 | 0.85 | biosample.attribute:geo_loc_name | China: Haikou |
| SAMN15195440 | location_region | Hainan | R1 | 0.60 | biosample.attribute:lat_lon | 20.03 N 110.18 E |
| SAMN15195432 | longitude | 110.1000 | R1 | 0.90 | biosample.attribute:lat_lon | 20.03 N 110.10 E |
| SAMN15195432 | sex | male | R2 | 0.70 | external.meta2db source | host_sex: male |
| SAMN15195433 | sex | female | R2 | 0.80 | paper.supp.41396_2021_1016_MOESM2_ESM.xlsx[Table_S1!Gender] | col0=C022; Gender=F |
| SAMN15195432 | smoking_status | current | R2 | 0.80 | paper.supp.41396_2021_1016_MOESM2_ESM.xlsx[Table_S1!Smoking] | col0=C021; Smoking=Y |
Sequencing
20 runs over 20 samples · mean 8.46 Gbp per run (median 8.59 Gbp, total 169.24 Gbp; 20 runs with a base count) · layout PAIRED 20 · platform ILLUMINA 20 · models Illumina HiSeq 4000 (20) · 85% of runs with a Sandpiper profile · first public 2020-06-11 – 2020-09-30
Authors (22)
Zhu Q first · Hou Q · Huang S · Ou Q · Huo D · Vázquez-Baeza Y · Cen C · Cantu V · Estaki M · Chang H · Belda-Ferre P · Kim HC · Chen K · Knight R · Zhang J last · Ma C first · Zhang Y · Jiang S · Teng F · Jiang Y first · Aton M · Lu YY last
Downloads
PRJNA602731.csv.gz (1.7 KB) · parquet (71.6 KB) — all 20 samples, every field with route and confidence · PRJNA602731_determinations.csv.gz (3.5 KB) — 228 evidence rows