Gut metagenomes in aortic aneurysm case-control study, China
18 fecal metagenome samples from adults (mostly) and elderly individuals in China, from a case-control study comparing ascending aortic aneurysm patients and healthy controls. machine-written summary
18 samples · 18 runs · CN · Adult · 2025 · 7.15 Gbp / sample · cohort Potential biomarkers for human Ascending aortic an
One study deposited as 4 BioProjects (72 catalog samples together): PRJNA1345173 · PRJNA1345175 · PRJNA1345176 · PRJNA1345179 · show together
Checked this project's papers and archive records yourself? Mark it human-verified.
what each source gave
| ✓ Sequence archive | 108 sample values (age, collection date, country, health condition, health condition detail, sex) |
| ○ Abstract / description | read; no usable statement |
| ○ Full text | read; no usable statement or table · PMC13539226 |
| ○ Supplementary tables | files read; no table could be matched to the samples |
| – External resources | not covered by the external resources we ingest |
| – User contribution | nothing uploaded yet |
| – Human verified | not yet checked by a person · I checked this project — verify it |
No Sandpiper profile for this project's samples yet.
| field | samples | coverage | R1 | R2 | R3 | R4 |
|---|---|---|---|---|---|---|
| age_category | 18 | 100% | ||||
| country | 18 | 100% | 18 | |||
| health_condition | 18 | 100% | 18 | |||
| subject_id | 0 | 0% | ||||
| age_at_collection_days | 18 | 100% | 18 | |||
| collection_date | 18 | 100% | 18 | |||
| health_condition_detail | 18 | 100% | 18 | |||
| sex | 18 | 100% | 18 |
- Potential biomarkers for human Ascending aortic aneurysm identified through metagenomic and metabolomic analyses: A case-control study. 2026 PMID 41429339 PMC13539226 unsure
Archive description
Introduction: Ascending aortic aneurysm (AsAA) is a high-risk cardiovascular condition recent research indicates a possible association between gut microbiota, plasma metabolites, and the pathogenesis of AsAA.
How this project entered the registry
Classified as human gut / stool / blood / tissue / internal fluids shotgun DNA metagenome of adult by sonnet_x2 with confidence 0.55. Assay shotgun_dna.
- host run.scientific_name · “Homo sapiens”
- body site study.description · “association between gut microbiota”
- body site sample.attr.tissue · “serum (n=18/18)”
- life stage study.title · “Ascending Aortic Aneurysm”
Evidence examples (one per field × route)
| sample | field | value | route | conf. | source | quote |
|---|---|---|---|---|---|---|
| SAMN52663317 | age_at_collection_days | 9496.5 | R1 | 0.85 | sample.attr.age | 26 |
| SAMN52663317 | collection_date | 2023 | R1 | 0.90 | biosample.attribute:collection_date | 2023 |
| SAMN52663317 | country | CN | R1 | 0.90 | sample.attr.geo_loc_name | China |
| SAMN52663317 | health_condition | healthy_control | R1 | 0.70 | sample.name_rule:alias | Control20 |
| SAMN52663317 | health_condition_detail | Control | R1 | 0.70 | sample.name_rule:alias | Control20 |
| SAMN52663317 | sex | female | R1 | 0.90 | sample.attr.sex | female |
Sequencing
18 runs over 18 samples · mean 7.11 Gbp per run (median 7.15 Gbp, total 128.06 Gbp; 18 runs with a base count) · layout PAIRED 18 · platform ILLUMINA 18 · models HiSeq X Ten (18) · 100% of runs with a Sandpiper profile · first public 2025-10-23
Downloads
PRJNA1345173.csv.gz (1.4 KB) · parquet (70.1 KB) — all 18 samples, every field with route and confidence · PRJNA1345173_determinations.csv.gz (1.4 KB) — 108 evidence rows