Gut metagenomics in aortic aneurysm case-control, China
16 fecal metagenome samples from adults and elderly individuals in China, part of a case-control study comparing ascending aortic aneurysm patients to healthy controls to identify gut microbiota and metabolite biomarkers. machine-written summary
16 samples · 16 runs · CN · Adult · 2025 · 7.22 Gbp / sample · cohort Potential biomarkers for human Ascending aortic an
One study deposited as 4 BioProjects (72 catalog samples together): PRJNA1345173 · PRJNA1345175 · PRJNA1345176 · PRJNA1345179 · show together
Checked this project's papers and archive records yourself? Mark it human-verified.
what each source gave
| ✓ Sequence archive | 96 sample values (age, collection date, country, health condition, health condition detail, sex) |
| ○ Abstract / description | read; no usable statement |
| ✓ Full text | 32 sample values (antibiotic exposure, location site) · PMC13539226 |
| ○ Supplementary tables | files read; no table could be matched to the samples |
| – External resources | not covered by the external resources we ingest |
| – User contribution | nothing uploaded yet |
| – Human verified | not yet checked by a person · I checked this project — verify it |
No Sandpiper profile for this project's samples yet.
| field | samples | coverage | R1 | R2 | R3 | R4 |
|---|---|---|---|---|---|---|
| age_category | 16 | 100% | ||||
| country | 16 | 100% | 16 | |||
| health_condition | 16 | 100% | 16 | |||
| subject_id | 0 | 0% | ||||
| age_at_collection_days | 16 | 100% | 16 | |||
| antibiotic_exposure | 16 | 100% | 16 | |||
| collection_date | 16 | 100% | 16 | |||
| detailed_location | 16 | 100% | ||||
| health_condition_detail | 16 | 100% | 16 | |||
| location_site | 16 | 100% | 16 | |||
| sex | 16 | 100% | 16 |
- Potential biomarkers for human Ascending aortic aneurysm identified through metagenomic and metabolomic analyses: A case-control study. 2026 PMID 41429339 PMC13539226 unsure
Archive description
This study enlisted 72 participants, comprising 44 individuals with AsAA and 28 healthy controls. All participants underwent examination for clinical features, and fecal and plasma samples were obtained for metagenomic and metabolomic studies.(2)
How this project entered the registry
Classified as human gut / stool / blood / tissue / internal fluids shotgun DNA metagenome of adult by sonnet_x2 with confidence 0.70. Assay shotgun_dna.
- host run.scientific_name · “Homo sapiens”
- body site study.description · “fecal and plasma samples were obtained”
- body site sample.attr.tissue · “serum (n=16/16)”
- life stage sample.attr.age · “52 (n=14/16)”
Evidence examples (one per field × route)
| sample | field | value | route | conf. | source | quote |
|---|---|---|---|---|---|---|
| SAMN52663335 | age_at_collection_days | 22280.2 | R1 | 0.70 | sample.attr.age | 61 |
| SAMN52663335 | antibiotic_exposure | no | R3 | 0.70 | paper.fulltext.methods | administration of antibiotics by any route prior to fecal sample collection |
| SAMN52663335 | collection_date | 2023 | R1 | 0.90 | biosample.attribute:collection_date | 2023 |
| SAMN52663335 | country | CN | R1 | 0.90 | sample.attr.geo_loc_name | China |
| SAMN52663335 | health_condition | cardiometabolic_other | R1 | 0.70 | sample.name_rule:alias | AsAA2 |
| SAMN52663335 | health_condition_detail | AsAA | R1 | 0.70 | sample.name_rule:alias | AsAA2 |
| SAMN52663335 | location_site | Fu Wai Hospital | R3 | 0.70 | paper.fulltext.methods | Fu Wai Hospital, Chinese Academy of Medical Sciences |
| SAMN52663335 | sex | male | R1 | 0.90 | sample.attr.sex | male |
Sequencing
16 runs over 16 samples · mean 7.18 Gbp per run (median 7.22 Gbp, total 114.94 Gbp; 16 runs with a base count) · layout PAIRED 16 · platform ILLUMINA 16 · models HiSeq X Ten (16) · 94% of runs with a Sandpiper profile · first public 2025-10-23
Downloads
PRJNA1345175.csv.gz (1.4 KB) · parquet (70.5 KB) — all 16 samples, every field with route and confidence · PRJNA1345175_determinations.csv.gz (1.8 KB) — 128 evidence rows