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PRJNA1345179 SRP632222

Gut microbiome in aortic aneurysm, China (case-control)

Potential Biomarkers for Human Ascending Aortic Aneurysm Identified Through Metagenomic and Metabolomic Analyses: A case-control study(4)

20 fecal samples from adults in China, comparing ascending aortic aneurysm patients to healthy controls in a case-control metagenomic and metabolomic study. machine-written summary

20 samples · 20 runs · CN · Adult · 2025 · 7.35 Gbp / sample · cohort Potential biomarkers for human Ascending aortic an

One study deposited as 4 BioProjects (72 catalog samples together): PRJNA1345173 · PRJNA1345175 · PRJNA1345176 · PRJNA1345179 · show together

Sources
✓Sequence archive 120○Abstract / description–Full text–Supplementary tables–External resources–User contribution–Human verified

Checked this project's papers and archive records yourself? Mark it human-verified.

what each source gave
✓ Sequence archive120 sample values (age, collection date, country, health condition, health condition detail, sex)
○ Abstract / descriptionread; no usable statement
– Full textno open-access full text linked
– Supplementary tablesno supplementary tables available (or none open access)
– External resourcesnot covered by the external resources we ingest
– User contributionnothing uploaded yet
– Human verifiednot yet checked by a person · I checked this project — verify it
Samples at a glance
1 country
Age
adult17
elderly3
Condition
cardiometabolic_other13
healthy_control7
Sex
male16
female4
Country
CN20
Body site
excluded20
Sequencing depth per sample · this project all projects
all projects, 0–0.03 Gbp: 25,080 samples (4 %)all projects, 0.03–0.1 Gbp: 17,066 samples (3 %)all projects, 0.1–0.3 Gbp: 29,179 samples (5 %)all projects, 0.3–1 Gbp: 47,044 samples (8 %)all projects, 1–3 Gbp: 124,983 samples (22 %)all projects, 3–10 Gbp: 253,728 samples (44 %)this project, 3–10 Gbp: 20 samplesall projects, 10–30 Gbp: 72,533 samples (13 %)all projects, 30–100 Gbp: 3,024 samples (1 %)all projects, 100–300 Gbp: 106 samples (0 %)all projects, ≥ 300 Gbp: 9 samples (0 %)project median 7.35 Gbp per sample0130Gbp
Community composition

No Sandpiper profile for this project's samples yet.

Field coverage
fieldsamplescoverageR1R2R3R4
age_category20 100%
country20 100%20
health_condition20 100%20
subject_id0 0%
age_at_collection_days20 100%20
collection_date20 100%20
health_condition_detail20 100%20
sex20 100%20
Papers (1)
  • Potential biomarkers for human Ascending aortic aneurysm identified through metagenomic and metabolomic analyses: A case-control study. 2026 PMID 41429339 PMC13539226 unsure
Details
Archive description

This study enlisted 72 participants, comprising 44 individuals with AsAA and 28 healthy controls. All participants underwent examination for clinical features, and fecal and plasma samples were obtained for metagenomic and metabolomic studies.(4)

How this project entered the registry

Classified as human gut / stool / blood / tissue / internal fluids shotgun DNA metagenome of adult and elderly by sonnet_x2 with confidence 0.65. Assay shotgun_dna.

  • host run.scientific_name · “Homo sapiens”
  • body site study.description · “fecal and plasma samples were obtained”
  • body site sample.attr.tissue · “serum (n=20/20)”
  • life stage sample.attr.age · “53 (n=16/20)”
  • life stage sample.attr.age · “66 (n=4/20)”
Evidence examples (one per field × route)
samplefieldvaluerouteconf.sourcequote
SAMN52663372age_at_collection_days20454.0R10.70sample.attr.age56
SAMN52663372collection_date2023R10.90biosample.attribute:collection_date2023
SAMN52663372countryCNR10.90sample.attr.geo_loc_nameChina
SAMN52663372health_conditioncardiometabolic_otherR10.70sample.name_rule:sample_aliasAsAA36
SAMN52663372health_condition_detailAsAAR10.70sample.name_rule:sample_aliasAsAA36
SAMN52663372sexmaleR10.90sample.attr.sexmale
Sequencing

20 runs over 20 samples · mean 7.29 Gbp per run (median 7.35 Gbp, total 145.76 Gbp; 20 runs with a base count) · layout PAIRED 20 · platform ILLUMINA 20 · models HiSeq X Ten (20) · 100% of runs with a Sandpiper profile · first public 2025-10-23

Authors (8)

Li M first · Gao S · Cheng J · Chen D · Li H · Zhang X · Wu C · Chang Y last

Downloads

PRJNA1345179.csv.gz (1.5 KB) · parquet (70.2 KB) — all 20 samples, every field with route and confidence · PRJNA1345179_determinations.csv.gz (1.6 KB) — 120 evidence rows

Samples (20 · every field this project has values for · hover a cell for its source)
Loading the sample table…