Gut metagenomes in aortic aneurysm, China, case-control
18 fecal metagenome samples from Chinese adults (one elderly), part of a case-control study comparing ascending aortic aneurysm patients and healthy controls for gut microbiota and metabolite biomarkers. machine-written summary
18 samples · 18 runs · CN · Adult · 2025 · 7.27 Gbp / sample · cohort Potential biomarkers for human Ascending aortic an
One study deposited as 4 BioProjects (72 catalog samples together): PRJNA1345173 · PRJNA1345175 · PRJNA1345176 · PRJNA1345179 · show together
Checked this project's papers and archive records yourself? Mark it human-verified.
what each source gave
| ✓ Sequence archive | 88 sample values (age, collection date, country, health condition, health condition detail, sex) |
| ✓ Abstract / description | 10 sample values (health condition detail) |
| ○ Full text | read; no usable statement or table · PMC13539226 |
| ○ Supplementary tables | files read; no table could be matched to the samples |
| – External resources | not covered by the external resources we ingest |
| – User contribution | nothing uploaded yet |
| – Human verified | not yet checked by a person · I checked this project — verify it |
No Sandpiper profile for this project's samples yet.
| field | samples | coverage | R1 | R2 | R3 | R4 |
|---|---|---|---|---|---|---|
| age_category | 18 | 100% | ||||
| country | 18 | 100% | 18 | |||
| health_condition | 8 | 44% | 8 | |||
| subject_id | 0 | 0% | ||||
| age_at_collection_days | 18 | 100% | 18 | |||
| collection_date | 18 | 100% | 18 | |||
| health_condition_detail | 18 | 100% | 8 | 10 | ||
| sex | 18 | 100% | 18 |
- Potential biomarkers for human Ascending aortic aneurysm identified through metagenomic and metabolomic analyses: A case-control study. 2026 PMID 41429339 PMC13539226 unsure
Archive description
This study enlisted 72 participants, comprising 44 individuals with AsAA and 28 healthy controls. All participants underwent examination for clinical features, and fecal and plasma samples were obtained for metagenomic and metabolomic studies.(3)
How this project entered the registry
Classified as human gut / stool / blood / tissue / internal fluids shotgun DNA metagenome of adult by sonnet_x2 with confidence 0.72. Assay shotgun_dna.
- host study.title · “Human Ascending Aortic Aneurysm”
- body site study.description · “fecal and plasma samples were obtained”
- body site sample.attr.tissue · “serum (n=18/18)”
- life stage sample.attr.age · “35 (n=16/18)”
Evidence examples (one per field × route)
| sample | field | value | route | conf. | source | quote |
|---|---|---|---|---|---|---|
| SAMN52663354 | age_at_collection_days | 23010.8 | R1 | 0.70 | sample.attr.age | 63 |
| SAMN52663354 | collection_date | 2023 | R1 | 0.90 | biosample.attribute:collection_date | 2023 |
| SAMN52663354 | country | CN | R1 | 0.90 | sample.attr.geo_loc_name | China |
| SAMN52663356 | health_condition | healthy_control | R1 | 0.70 | sample.name_rule:library_names | Control3 |
| SAMN52663356 | health_condition_detail | Control | R1 | 0.70 | sample.name_rule:library_names | Control3 |
| SAMN52663354 | health_condition_detail | mixed_case_control: Case-control study: 44 AsAA patients vs 28 healthy controls | R4 | 0.50 | paper.abstract | 44 individuals with AsAA and 28 healthy controls |
| SAMN52663354 | sex | male | R1 | 0.90 | sample.attr.sex | male |
Sequencing
18 runs over 18 samples · mean 7.15 Gbp per run (median 7.27 Gbp, total 128.78 Gbp; 18 runs with a base count) · layout PAIRED 18 · platform ILLUMINA 18 · models HiSeq X Ten (18) · 94% of runs with a Sandpiper profile · first public 2025-10-23
Downloads
PRJNA1345176.csv.gz (1.5 KB) · parquet (70.3 KB) — all 18 samples, every field with route and confidence · PRJNA1345176_determinations.csv.gz (1.5 KB) — 98 evidence rows