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Antibiotic intervention and recovery cohorts

Study design · collection id antibiotic-intervention-cohorts

Studies in which antibiotics were administered by design or documented as the exposure of interest, with before/after shotgun sampling: healthy-volunteer courses (cefprozil, ciprofloxacin, beta-lactams), probiotic-after-antibiotic trials, travellers'-diarrhoea regimens, mass azithromycin distribution and preterm-infant exposure.

Open in the sample explorer (5,520 samples)

13
studies with member samples
5,520
member samples in this release

Membership rule

StudiesPRJEB8094, PRJNA974858, PRJNA1025016, PRJEB105465, PRJNA922086, PRJNA1074135, PRJNA450709 (not in this release), PRJEB27325 (not in this release), PRJNA945408, PRJNA1106565, PRJNA1364313, PRJNA917819, PRJNA993161, PRJNA807448, PRJNA1337442

Listed studies with no member samples after the filters: PRJNA450709, PRJEB27325.

Composition

Age category
adult2,934
infant1,223
unknown1,041
neonate266
elderly54
adolescent2
Country
US2,386
SE548
AU459
NE450
FR335
CN296
Health condition
healthy_control Healthy / control3,400
gi_infection_or_diarrhoea GI infection / diarrhoea (incl. C. difficile)416
intervention_cohort Intervention cohort (drug335
other_infection Other infection (HIV263
Lifestyle
military Military personnel / training416

Member studies (13)

StudyTitleMember samplesFirst public
PRJNA974858Temporal shotgun sequencing of the gut microbiota of healthy adults taking ciprofloxacin1,0402024
PRJNA1106565Antibiotic exposure is associated with minimal gut microbiome perturbations in healthy term infants6692024
PRJEB105465Effects of antibiotic treatment on normal intestinal flora (ARG-study)5482026
PRJNA807448The Antibiotics and Immune Responses Study4592025
PRJNA1337442Effect of Mass Azithromycin Distribution on Antibiotic Resistance in the Gut and Nasopharynx: A Cluster-Randomized Trial4502026
PRJNA945408Impact of antibiotic regimens for the prevention and treatment of travelers diarrhea Prevent TD and TrEAT TD4162023
PRJNA1364313Antibiotic impact on preterm infant microbiome maturation3612025
PRJNA922086Deleterious impact of beta-lactam antibiotics on intestinal microbiome of human healthy volunteers and protection with co-administration of the DAV132 colon-targeted adsorbent.3352024
PRJNA993161Impact of complex oligosaccharides and a probiotic on the antibiotic-treated human microbiome3162023
PRJNA917819Probiotics modulation of post-antibiotic gut microbiome in healthy population2962025
PRJNA1074135Long-term effects of ciprofloxacin treatment on the gastrointestinal and oropharyngeal microbiome are more pronounced after longer antibiotic courses2952024
PRJNA1025016Commensal Antimicrobial Resistance Mediates Microbiome Resilience to Antibiotic Disruption2632024
PRJEB8094The initial state of the human gut microbiome determines its reshaping by antibiotics722015

References