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Faecal microbiota transplantation trials

Study design · collection id fmt-trials

Randomised and single-arm FMT trials with shotgun follow-up across indications — ulcerative colitis, IBS, obesity, Parkinson's disease, hypertension, cirrhosis, diabetic neuropathy, immunotherapy resistance in melanoma and lung cancer, and CPE decolonisation — plus FMT donor series.

Open in the sample explorer (5,376 samples)

19
studies with member samples
5,376
member samples in this release

Membership rule

StudiesPRJNA637785, PRJEB68317, PRJNA1450848, PRJEB72385, PRJEB61882, PRJNA871036, PRJEB94043, PRJNA737472, PRJEB58035, PRJNA1289847, PRJNA672867, PRJEB53551, PRJEB66493, PRJEB47061, PRJEB65418, PRJEB102130, PRJEB26357, PRJNA491657, PRJNA448876

Selected from study titles containing FMT / faecal microbiota transplantation; metatranscriptome and biopsy companions (PRJEB26472–26474) were left out.

Composition

Age category
adult4,428
unknown680
adolescent186
elderly82
Country
CN1,138
US1,049
FI549
NZ430
GB278
HK275
Health condition
ulcerative_colitis Ulcerative colitis1,140
cardiometabolic_other Other cardiometabolic (hypertension751
healthy_control Healthy / control656
other_cancer Other cancer (incl. immunotherapy cohorts)560
neurological_psychiatric Neurological / psychiatric (PD416
ibs Irritable bowel syndrome404

Member studies (19)

StudyTitleMember samplesFirst public
PRJEB72385Fecal Microbiota Transplantation on Hypertension: an exploratory, multi-center, randomized, blinded, placebo-controlled trial7512024
PRJNA448876Dense longitudinal metagenomic analysis of the gut microbiome of FMT donors4692020
PRJNA637785Multi-donor FMT to treat adolescents with severe obesity (The Gut Bugs Trial)4302021
PRJEB68317Fecal microbiota transplantation in Parkinson's disease4162024
PRJNA1450848Improved Efficacy of Fecal Microbiota Transplantation for Ulcerative Colitis with Non-urbanized Donors3872026
PRJEB26357ShotGun BACTERIAL AND FUNCTIONAL DETERMINANTS OF OUTCOME IN FAECAL MICROBIOTA TRANSPLANTATION FOR ACTIVE ULCERATIVE COLITIS2842018
PRJEB61882PROFIT Trial: FMT in cirrhosis2782024
PRJNA871036Faecal Microbiota Transplantation in patients with irritable bowel syndrome: a randomized, double-blind, placebo-controlled study2752024
PRJEB94043Clinical trial (TACITO) for the evaluation of the efficacy of targeted of fecal microbiota transplantation (FMT) in improving response rates to immune checkpoint inhibitors (ICIs) in subjects with treatment-naïve metastatic renal cell carcinoma.2552025
PRJNA737472Microbiome sequencing of ulcerative colitis patients receiving fecal microbiota transplantation2242022
PRJEB58035Patient samples from lyophilised oral faecal microbiota transplantation for ulcerative colitis (LOTUS) study shotgun2212024
PRJNA1289847Gut microbiota composition of patients in FMT-LUMINate clinical trial2162025
PRJNA672867Effectiveness of Fecal Microbiota Transplant together with PD-1 blockade in overcoming resistance to anti-PD-1 therapy in advanced melanoma patients2162020
PRJEB53551FMT alleviates peripheral neuropathy in patients with diabetes mellitus2122024
PRJEB66493A Randomised Placebo-Controlled Trial of Faecal Microbiota Transplantation in Patients with Chronic Pouchitis – MicroPouch study1772024
PRJEB47061Fecal microbiota transplantation for treatment of ulcerative colitis1602021
PRJNA491657Microbiota of allo-HSCT patients and in the setting of Autologous Fecal Microbiota Transplant (auto-FMT) at MSKCC Raw sequence reads1402020
PRJEB65418Fecal microbiota transplantation in irritable bowel syndrome patients1332024
PRJEB102130Shotgun metagenomics of FMT for CPE decolonization1322026

References