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All liver disease samples
Disease reference sets · collection id liver-disease-samples
Every gut sample whose curated health_condition is liver disease (cirrhosis, hepatitis, hepatocellular carcinoma, hepatic encephalopathy), across all studies.
Open in the sample explorer (5,480 samples)
50
studies with member samples
5,480
member samples in this release
Membership rule
| health_condition | liver_disease |
| body_site_class | primary |
Composition
Age category
| unknown | 2,777 |
| adult | 2,427 |
| elderly | 173 |
| child | 93 |
| adolescent | 10 |
Country
| US | 2,707 |
| CN | 690 |
| DK | 350 |
| HU | 302 |
| ES | 221 |
| DE | 176 |
Health condition
| liver_disease Liver disease (cirrhosis | 5,480 |
Member studies (50)
| Study | Title | Member samples | First public |
|---|---|---|---|
| PRJNA912122 | Lactulose-mediated Bifidobacteria expansion promotes a beneficial fecal metabolite profile that is associated with exclusion of antibiotic-resistant pathogens and improved outcomes in advanced liver disease | 850 | 2022 |
| PRJEB102033 | Lantibiotic-producing bacteria impact microbiome resilience and colonization resistance | 571 | 2025 |
| PRJEB76661 | Metagenomic analysis of the gut microbiome in patients with alcohol-related liver disease | 350 | 2024 |
| PRJEB89898 | Metagenomic sequences of the fecal microbiome from patients with decompensated cirrhosis and ACLF | 302 | 2025 |
| PRJNA1425466 | Stool metagenome in primary billiary cholangitis (PBC) | 280 | 2026 |
| PRJNA1425460 | Stool metagenome in primary sclerosing cholangitis (PSC) | 245 | 2026 |
| PRJNA1372070 | Hepatocellular Carcinoma Cohort Metagenomics | 196 | 2026 |
| PRJEB40200 | Alterations in gut microbiome in cirrhosis as assessed by quantitative metagenomics. Relationship with acute-on-chronic liver failure and mortality and prognosis. | 181 | 2020 |
| PRJNA1227423 | Metagenomic shotgun sequencing data of fecal samples from a liver disease cohort | 176 | 2025 |
| PRJEB73985 | Oat beta glucan versus iso dietary fiber or placebo in MASLD: A multicenter, randomized, placebo-controlled dietary study | 175 | 2025 |
| PRJEB6337 | Liver cirrhosis occurs as a consequence of many chronic liver diseases that are prevalent worldwide. Previous studies have shown an association between the gut microbiota and liver complications such as cirrhosis and other liver injuries. We therefore undertook a whole gut microbiome wide association study of stool samples from 98 liver cirrhosis patients and 83 healthy controls to characterise the faecal microbial communities and their functional composition. In total, we generated 860 Gb of high-quality sequence data and built a reference gene set for the liver cirrhosis cohort containing 2.69 million genes, 36.1% of which was not covered by previously published gene catalogues. | 169 | 2014 |
| PRJNA1039781 | Fecal metabolite profiling identifies liver transplant recipients at risk for postoperative infection | 143 | 2023 |
| PRJNA1491285 | Gut microbiota in patients with cirrhosis and portal hypertension receiving lactulose | 143 | 2026 |
| PRJDB28938 | Multi-omics reveal host-microbiota interactions in primary biliary cholangitis (PRJCA018532) | 132 | 2026 |
| PRJNA1184735 | Fecal butyrate and deoxycholic acid concentrations correlate with mortality in hospitalized patients with liver disease | 122 | 2024 |
| PRJEB38481 | Liver Cirrhosis cohort | 90 | 2021 |
| PRJNA608022 | human viral metagenome Raw sequence reads | 88 | 2020 |
| PRJNA1203401 | Gut microbiota predicts treatment response to empagliflozin among MASLD patients without diabetes mellitus | 87 | 2025 |
| PRJNA622386 | Human feces viral metagenome raw sequence reads associated with NAFLD | 86 | 2020 |
| PRJNA546034 | NAFLD Microbiome | 86 | 2019 |
| PRJNA766067 | The Mucosally-Adherent Rectal Microbiota Contains Features Unique to Alcohol-Related Cirrhosis | 84 | 2021 |
| PRJNA1317556 | Microbiome and metabolome characteristics of the small intestine in patients with ACLF | 80 | 2025 |
| PRJEB14215 | The role of the intestinal microflora in non-alcoholic fatty liver disease (NAFLD) (FP7) | 73 | 2018 |
| PRJNA1308792 | Microbial diversity in patients with alcoholic liver disease | 56 | 2025 |
| PRJNA1234627 | Resistant starch intervention in patients with MASLD | 55 | 2025 |
| PRJNA1104421 | Serum Bile Acids profiles are altered without change of the Gut Microbiota composition following a seven-day prednisolone therapy in severe alcoholic hepatitis | 54 | 2024 |
| PRJNA1372073 | Hepatocellular Carcinoma Cohort Metagenomics | 52 | 2026 |
| PRJNA1111312 | Shotgun metagenomics reveals Bacteroides stercoris as a fecal biomarker depleted in late-stage hepatocellular carcinoma | 51 | 2024 |
| PRJNA373901 | Novel gut-microbiota based metagenomic signature for advanced fibrosis in nonalcoholic fatty liver disease | 50 | 2017 |
| PRJNA1398904 | Enterococcus faecium Driven Metabolic Dysbiosis is Linked to Mortality following Liver Transplant | 42 | 2026 |
| PRJEB11419 | American Gut Project | 40 | 2015 |
| PRJNA1377628 | Decoding the microbiome and resistome of advanced chronic liver disease through long-read metagenomics | 36 | 2026 |
| PRJNA1144402 | Patients Infected with the Hepatitis D Virus have a Unique Gut Microbiome with Distinguishing Microbial and Functional Features | 35 | 2026 |
| PRJEB60097 | Microbiome in health and disease | 31 | 2023 |
| PRJNA1177516 | Changes in Fecal Microbiota in Adults with Cystic Fibrosis with 6 Months of CFTR Modulator Therapy Elexacaftor/Tezacaftor/Ivacaftor (ETI) | 30 | 2025 |
| PRJNA730640 | The composition of gut microbiota in biliary atresia | 30 | 2021 |
| PRJNA1172418 | Development of a model predicting 90-day survival in severe alcohol-related hepatitis using a retrospective cohort | 30 | 2025 |
| PRJEB18041 | "Shotgun" gut metagenomes of the patients with alcohol dependence syndrome and alcoholic liver cirrhosis | 27 | 2016 |
| PRJNA1092365 | Raw data used for stduying interaction between bile acid and gut microbiome | 23 | 2025 |
| PRJNA1334189 | The gut microbiome of human liver diseases | 22 | 2025 |
| PRJNA970820 | human gut metagenome Genome sequencing and assembly | 21 | 2023 |
| PRJNA517801 | WGS_Liver_disease | 21 | 2019 |
| PRJNA1438274 | Proximity-ligation metagenomics of rCDI and Cirrhosis Patients | 19 | 2026 |
| PRJNA328258 | feces metagenome Metagenome | 17 | 2022 |
| PRJDB10484 | Gut microbial species responsible for hyperammonemia-related urease activity in hepatic encephalopathy patients | 12 | 2022 |
| PRJNA1167913 | Metagenomic sequencing of human fecal samples from NAFLD and non-NAFLD patients infected with HIV | 6 | 2024 |
| PRJDB5180 | A metagenomic approach for acute cholecystitis patients enables pathogen detection and rapid diagnostics | 5 | 2017 |
| PRJNA1468588 | Gut microbiome dynamics in a primary sclerosing cholangitis patient treated with vancomycin | 4 | 2026 |
| PRJNA624763 | Shotgun metagenomics of human gut microbiota in China high longevity area | 1 | 2020 |
| PRJNA850529 | Host factors associated with gut mycobiome structure | 1 | 2023 |